Dear Colleagues, 

Engineered tissues can be used to replace diseased or damaged tissues, or as in vitro models of development, disease, and drug response. In order to achieve an effective regeneration or modelling, engineered tissues should ideally be produced with structural elements that mimic their natural counterparts. These features include anisotropic organization of cells and matrix fibers, gradient and zonal tissue distributions, and perfusable, multiscale vascular networks.

Many researchers are developing innovative methods for spatially redistributing tissue engineering components (cells, biomaterials, growth factors) in order to generate complex tissue structures. These efforts are often highly interdisciplinary, bringing techniques from physical sciences and engineering to exert control over tissue culture processes. The cross-cutting nature of this field can create barriers to adoption, which can be addressed by disseminating detailed protocols to the research community.

The Journal of Biological Methods (JBM) is pleased to announce a call for papers for an upcoming special issue entitled “Methods for Engineering Complex Tissues.” This special issue will be guest edited by Dr. James Armstrong at Imperial College London.

Topics of interest include techniques that have been used to spatially redistribute tissue engineering components before or during a culture process. This includes 3D bioprinting, controlled fluidic mixing, advanced electrospinning, convective stretching, controlled phase changes, post-modification, self-assembly (e.g., those governed by surface tension, geometric recognition, or molecular recognition), textile-based assembly, magnetic or electric field alignment, acoustic cell patterning, and photopatterning.

We emphasize that working protocols for this special issue that may have already been published in part in previous reports from prospective authors. However, we encourage all manuscript formats, including Articles, Benchmarks, Protocols, Resources, and Reviews. Please contact Dr. Armstrong ( or with questions or inquiries about suitability. If your method is accepted for publication, a 20% discount on the Article Processing Charge (APC) will be applied, bringing the total cost of publication down to $800 USD. JBM is a PubMed-indexed journal and all articles are made open access

We look forward to your submission!